Cars

Commonly abbreviated as Hb Hemoglobin or Heamoglobin is the iron containing oxygen in our red blood cells which transport metalloproteins All mammals on earth have hemoglobin as it is a necessary function in the blood It contains globin apoprotien a
Commonly abbreviated as Hb Hemoglobin or Heamoglobin is the iron containing oxygen in our red blood cells which transport metalloproteins All mammals on earth have hemoglobin as it is a necessary function in the blood It contains globin apoprotien and four heme groups organic molecules with one atom of iron attached to eachThe gene for the hemoglobin protien can sometimes mutate This occurence results in one or more of many diseases but most commonly turns into Thalassemia or Sicklecell disease

Heme groups are located in each subunit of a hemoglobin molecule A heme group consists of a single iron atom held in a heterocyclic ring commonly known as a porphyrin Oxygen binding takes place in this iron atom The one iron atom binds itself equally to all four nitrogens in the center of the heterocyclic ring which lies on one plane In addition two bonds perpendicular to the plane on each side are sometimes formed with the iron to produce the fifth and sixth positions

The name hemoglobin comes from heme and globin Globin is a generic term used for a globular protein Since any single subunit of hemoglobin is made of a heme imbedded in a globular protein the name makes perfect sense There are many heme containing hemoglobins and proteins Hemoglobin A is the most commonly known

In adults the most common hemoglobin is a tetramer hemoglobin containing 4 subunit proteins called hemoglobin A The subunits are similar in structure and approximatly the same size Each subunits molecular weight is about 16000 daltons for a total combined molecular weight in the tetramer of approximatly 64000 daltons A single heme is contained in each subunit of hemoglobin so that the overall binding capacity of human adults hemoglobin for oxygen is four oxygen molecules